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Adeno-Associated Virus (AAV) Vectors

Adeno-Associated Virus (AAV) Vectors

Adeno-associated viruses (AAVs) are a class of simple, non-enveloped, single-stranded DNA-deficient viruses capable of infecting both dividing and non-dividing cells. They can package large genes, making them a preferred tool for gene overexpression. AAVs are characterized by good safety, a broad host cell range, low immunogenicity, and long-term expression of exogenous genes in vivo. Shenzhen Cell Valley provides adeno-associated virus vectors of various specifications and serotypes, including single-promoter single-gene, single-promoter multi-gene, and dual-promoter multi-gene subtypes.
Description

Highlights

1. High safety and low pathogenicity to humans;
2. Infectious on both dividing and non-dividing cells;
3. Effectively proliferates;
4. High viral titer.

Overview

•  Adeno-associated virus (AAV) is a member of the parvoviridae family. It is a type of non-replicating, non-enveloped, icosahedral microvirus with a diameter of approximately 20-26 nm, containing about 4.7 kb of linear single-stranded DNA as its genome. The recombinant adeno-associated virus (rAAV)vectoris a gene vector modified from non-pathogenic wild-typeAAV. Due to its diversity, extremely low immunogenicity, high safety, broad host cell range (infecting both dividing and non-dividing cells), strong dispersibility, and long in vivo gene expression time, rAAVisconsidered one of the most promising vectors for gene research and gene therapy.

AAV genome structure


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Working hours: Monday to Friday, 9:00-18:00

Contact：Ms. Lai

Email：laijiaqi@61zoeshop.com

Address：No. 1, Rongtian Road, Jinsha Community, Kengzi Street, Pingshan District, Shenzhen, China (Hepure Biomedical Ecological Park)

Cell Valley Group is a leading CGT infrastructure platform in China. We capitalize on the strategic window opened by Decree No. 818 to bridge the gap between clinical research and commercialization.

We pioneer the "Hospital to Industry" (H2I) model. Basically, we act as the core partner for hospitals, providing a one-stop solution for new biomedical tech—covering process development, GMP manufacturing, QC, and commercial rollout. Our mission is to push China's CGT sector from pure R&D into a standardized, scalable industry.
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